The way SSRIs work is by increasing serotonin in the brain. In particular, they are both selective serotonin reuptake inhibitors ( SSRIs). Zoloft and Paxil are both antidepressant drugs. Zoloft is FDA-approved as a treatment for the following disorders: When the FDA approves a medicine, the drug’s benefits outweigh any known or prospective risks. The FDA has approved Zoloft for treating various medical conditions, including anxiety, depression, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD). It works by raising the level of the neurotransmitter serotonin in the brain. It belongs to the category of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). 2 It is approved by the FDA to treat various conditions, including OCD and depression in adults, as well as OCD in children and adolescents between the ages of 6 and 17. The antidepressant medication sertraline is known by its brand name, Zoloft. Paxil is FDA-approved as a treatment for the following disorders: When the FDA approves a drug, it means that the data on the drug’s safety and the drug’s benefits outweigh its known and possible risks for the people it is meant for. Paxil is a medication approved by the FDA for treating various conditions, including clinical depression and specific anxiety disorders. Paxil’s ability to do this contributes to an overall improvement in mood and a reduction in the symptoms of various mental health conditions, including anxiety, depression, and others. 1 The effectiveness of SSRIs can be attributed to their ability to boost serotonin levels, a chemical already present in the brain. Paxil is a brand name that contains the active ingredient paroxetine and is an SSRI that is FDA-approved to treat depression, anxiety, and other mental disorders in adults 18 years and older.

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